Delmonico Francis L, Sheehy Ellen, Marks William H, Baliga Prabhakar, McGowan Joshua J, Magee John C
Massachusetts General Hospital, Boston, MA, USA.
Am J Transplant. 2005 Apr;5(4 Pt 2):862-73. doi: 10.1111/j.1600-6135.2005.00832.x.
This article discusses issues directly related to the organ donation process, including donor consent, donor medical suitability, non-recovery of organs, organs recovered but not transplanted, expanded criteria donors (ECD), and donation after cardiac death (DCD). The findings and topics covered have important implications for how to evaluate and share best practices of organ donation as implemented by organ procurement organizations (OPOs) and major donor hospitals in the same donation service areas (DSAs). In 2002 and 2003, US hospitals referred more than one million deaths or imminent deaths to the OPOs of their DSA. Referrals increased by nearly 10% from 2002 to 2003 (1,022,280 to 1,121,392). Donor consents have increased by about 5% and the number of total deceased donors has risen from 6,187 to 6,455. Since multiple organs are recovered from most donors, this increase allowed more than 500 additional wait-listed candidates to receive an organ transplant than in the prior year. Non-traditional donor sources have experienced a large rate of increase; in 2003 the number of ECD kidney donors increased by 8% and the number of DCD donors increased by 43%, from 189 donors in year 2002 to 271 donors in 2003.
本文讨论了与器官捐赠过程直接相关的问题,包括捐赠者同意、捐赠者医学适宜性、器官未获取、获取但未移植的器官、扩大标准捐赠者(ECD)以及心脏死亡后捐赠(DCD)。所涵盖的研究结果和主题对于如何评估和分享器官采购组织(OPO)和同一捐赠服务区(DSA)内主要捐赠医院实施的器官捐赠最佳实践具有重要意义。在2002年和2003年,美国医院向其DSA的OPO转诊了超过100万例死亡或濒死病例。从2002年到2003年,转诊病例增加了近10%(从1,022,280例增至1,121,392例)。捐赠者同意率增加了约5%,总死亡捐赠者数量从6,187例增至6,455例。由于大多数捐赠者可获取多个器官,这一增长使得等待名单上接受器官移植的候选者比上一年增加了500多名。非传统捐赠来源的增长幅度很大;2003年,ECD肾脏捐赠者数量增加了8%,DCD捐赠者数量增加了43%,从2002年的189名捐赠者增至2003年的271名捐赠者。