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艾哈迈德瓣膜植入术治疗慢性葡萄膜炎继发青光眼。

Ahmed valve implantation in glaucoma secondary to chronic uveitis.

作者信息

Ozdal P C, Vianna R N G, Deschênes J

机构信息

Department of Ophthalmology, Uveitis Service, McGill University, Montréal, Canada.

出版信息

Eye (Lond). 2006 Feb;20(2):178-83. doi: 10.1038/sj.eye.6701841.

Abstract

PURPOSE

To evaluate the efficacy of Ahmed valve (AV) implantation in patients with uveitic glaucoma.

METHODS

In total, 18 patients (19 eyes) with glaucoma secondary to chronic uveitis, who underwent AV implantation were retrospectively reviewed. Visual acuity, intraocular pressure (IOP), and glaucoma medications at the most recent examination prior to surgery, were compared with those of last postoperative examination. The surgical success was defined as IOP less than 21 mmHg and greater than 4 mmHg without loss of light perception and visually devastating complications at the last postoperative examination. Decrease in the number of glaucoma medications was also a criterion for surgical success.

RESULTS

The mean follow-up period was 26+/-9.7 months. The mean preoperative and postoperative IOPs were 33.3+/-9.7 (range, 20-57) mmHg and 17.3+/-10.8 (range, 6-40) mmHg respectively (P<0.0001). The mean number of antiglaucoma medications was 3.5+/-0.8 (range, 2-5) preoperatively and 1.4+/-1.3 (range, 0-4) postoperatively (P<0.0001). Valve occlusion (five eyes, 26.3%) was the most commonly observed complication. Surgical success was achieved in 13 eyes (68.4%). The cumulative probability of success was 94.4% at 1 year and 60% at 2 years. Five eyes (26.3%) with IOP greater than 21 mmHg and one (5.3%) with corneal decompensation requiring penetrating keratoplasty were considered as failures.

CONCLUSIONS

The implantation of AV is an effective surgical procedure for the management of uveitic glaucoma. The inflammatory background might contribute to the occurrence of valve occlusion, which is the most common complication. Prevention of this complication is an essential factor for improving the surgical outcome.

摘要

目的

评估艾哈迈德引流阀(AV)植入术治疗葡萄膜炎性青光眼患者的疗效。

方法

回顾性分析18例(19只眼)接受AV植入术的慢性葡萄膜炎继发青光眼患者。将手术前最近一次检查时的视力、眼压(IOP)和青光眼用药情况与术后最后一次检查时的情况进行比较。手术成功定义为术后最后一次检查时眼压低于21 mmHg且高于4 mmHg,无光感丧失和严重视力损害并发症。青光眼用药数量减少也是手术成功的标准。

结果

平均随访期为26±9.7个月。术前和术后平均眼压分别为33.3±9.7(范围20 - 57)mmHg和17.3±10.8(范围6 - 40)mmHg(P<0.0001)。术前平均抗青光眼药物数量为3.5±0.8(范围2 - 5)种,术后为1.4±1.3(范围0 - 4)种(P<0.0001)。引流阀阻塞(5只眼,26.3%)是最常见的并发症。13只眼(68.4%)手术成功。1年时成功的累积概率为94.4%,2年时为60%。5只眼(26.3%)眼压高于21 mmHg,1只眼(5.3%)因角膜失代偿需要穿透性角膜移植术,被视为手术失败。

结论

AV植入术是治疗葡萄膜炎性青光眼的有效手术方法。炎症背景可能导致引流阀阻塞的发生,这是最常见的并发症。预防该并发症是改善手术效果的关键因素。

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