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葡萄膜炎性青光眼小梁切除术、艾哈迈德分流术和贝尔维尔德分流术手术效果的比较。

Comparison of surgical outcomes of trabeculectomy, Ahmed shunt, and Baerveldt shunt in uveitic glaucoma.

作者信息

Chow Audrey, Burkemper Bruce, Varma Rohit, Rodger Damien C, Rao Narsing, Richter Grace M

机构信息

Department of Ophthalmology, USC Roski Eye Institute, Keck Medicine of University of Southern California, 1450 San Pablo Street, Suite 4700, Los Angeles, CA, 90033, USA.

Department of Ophthalmology, Kaiser Permanente Los Angeles Medical Center, 1515 N. Vermont Ave, 7th floor, Los Angeles, CA, 90027, USA.

出版信息

J Ophthalmic Inflamm Infect. 2018 Jun 18;8(1):9. doi: 10.1186/s12348-018-0150-y.

Abstract

BACKGROUND

Uveitis is defined as a collection of syndromes involving intraocular inflammation which can lead to pain, tissue damage, and vision loss. Ophthalmic surgery in uveitis patients can be challenging due to inflammation-induced fibrosis and scarring. Trabeculectomy and implantation of glaucoma drainage devices (aqueous shunts) have been used in surgical management of uveitic glaucoma, however there is a paucity of literature examining the comparative results of these entities in this unique setting. The purpose of this retrospective comparative study is to compare clinical outcomes of trabeculectomy with MMC, Ahmed shunt, and Baerveldt shunt surgery specifically in uveitic glaucoma.

RESULTS

Median IOP, IOP reduction, glaucoma medication use, and visual acuity at 6- and 12-month follow-up were similar across groups. Postoperative hypotony rate was significantly different across trabeculectomy (53%), Baerveldt (24%), and Ahmed (18%) groups (p = 0.027); other complication rates were similar. Baerveldt eyes had a lower failure rate compared to trabeculectomy (p = 0.0054) and Ahmed (p = 0.0008) eyes.

CONCLUSIONS

While there was no difference in IOP reduction between trabeculectomy, Ahmed, and Baerveldt, Baerveldt eyes had the lowest failure rate.

摘要

背景

葡萄膜炎被定义为一组涉及眼内炎症的综合征,可导致疼痛、组织损伤和视力丧失。由于炎症引起的纤维化和瘢痕形成,葡萄膜炎患者的眼科手术具有挑战性。小梁切除术和青光眼引流装置(房水分流器)植入已用于葡萄膜炎性青光眼的手术治疗,然而,在这种独特情况下,研究这些手术相对结果的文献较少。这项回顾性比较研究的目的是比较小梁切除术联合丝裂霉素C、艾哈迈德分流器和贝尔维尔德分流器手术在葡萄膜炎性青光眼中的临床结果。

结果

各治疗组在6个月和12个月随访时的眼压中位数、眼压降低幅度、青光眼药物使用情况及视力相似。小梁切除术组(53%)、贝尔维尔德分流器组(24%)和艾哈迈德分流器组(18%)的术后低眼压发生率有显著差异(p = 0.027);其他并发症发生率相似。与小梁切除术组(p = 0.0054)和艾哈迈德分流器组(p = 0.0008)相比,贝尔维尔德分流器组的失败率更低。

结论

虽然小梁切除术、艾哈迈德分流器和贝尔维尔德分流器在降低眼压方面没有差异,但贝尔维尔德分流器组的失败率最低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/39a2/6006003/a6d6928085de/12348_2018_150_Fig1_HTML.jpg

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