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经巩膜下Tenon囊注射曲安奈德治疗息肉状脉络膜血管病变后的视力改善

Visual improvement following trans-Tenon's retrobulbar triamcinolone acetonide infusion for polypoidal choroidal vasculopathy.

作者信息

Okubo Akiko, Ito Motoko, Kamisasanuki Taro, Sakamoto Taiji

机构信息

Department of Ophthalmology, Kagoshima University Graduate School of Medical and Dental Sciences, 8-35-1 Sakuragaoka, Kagoshima 890-8520, Japan.

出版信息

Graefes Arch Clin Exp Ophthalmol. 2005 Aug;243(8):837-9. doi: 10.1007/s00417-005-1125-x. Epub 2005 Mar 11.

Abstract

PURPOSE

To report a case of polypoidal choroidal vasculopathy (PCV) that was successfully treated by sub-Tenon's infusion of triamcinolone acetonide (TA).

METHODS

A 56-year-old Japanese man had PCV in his left eye with vision of 20/32. Fluorescein angiography demonstrated a hyper-fluorescent spot, and indocyanine green angiography showed marked leakage of dye from the polypoidal vessel. Optical coherence tomography showed anterior protrusion of highly reflective layers and subretinal fluid.

RESULTS

The patient underwent trans-Tenon's retrobulbar infusion of 12 mg TA. Subsequently, the reddish-orange lesion decreased in size and elevation with complete resolution of the serous retinal detachment, and visual acuity improved to 20/20. Visual acuity remained good through a 15-month follow-up during which the patient was free of endophthalmitis and elevated intraocular pressure.

CONCLUSIONS

Trans-Tenon's retrobulbar TA infusion is potentially effective in treating PCV.

摘要

目的

报告1例经球后Tenon囊下注射曲安奈德(TA)成功治疗的息肉状脉络膜血管病变(PCV)病例。

方法

一名56岁日本男性左眼患有PCV,视力为20/32。荧光素血管造影显示一个高荧光点,吲哚菁绿血管造影显示染料从息肉状血管明显渗漏。光学相干断层扫描显示高反射层向前突出和视网膜下液。

结果

患者接受了经Tenon囊的球后12mg TA注射。随后,红橙色病变大小和隆起度减小,浆液性视网膜脱离完全消退,视力提高到20/20。在15个月的随访期间视力保持良好,在此期间患者未发生眼内炎和眼压升高。

结论

经Tenon囊的球后TA注射可能对治疗PCV有效。

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