Jan Ahmed, Vora Kashyap, Sándor George K B
University of Toronto, Toronto, Ontario.
J Can Dent Assoc. 2005 Mar;71(3):165-8.
Burkitt's lymphoma is an undifferentiated non-Hodgkin's B-cell lymphoma. Three clinical subtypes are recognized: African (endemic), American (sporadic) and HIV associated. Sporadic Burkitt's lymphoma is a rare malignancy among western populations. This report describes a case of sporadic Burkitt's lymphoma of the jaws with an alarmingly rapid spread associated with acute renal failure. This type of rapid progression bespeaks the need for prompt recognition and life-saving referral by the dental practitioner. The clinical features of Burkitt's lymphoma involving the jaws include severely hypermobile, ectopically displaced and supra-erupted teeth. The purpose of this case report and review of the literature is to illustrate the clinical and histopathologic features of Burkitt's lymphoma to help clinicians recognize such cases readily and facilitate prompt and potentially life-saving referral.
伯基特淋巴瘤是一种未分化的非霍奇金B细胞淋巴瘤。已确认有三种临床亚型:非洲型(地方性)、美洲型(散发性)和与HIV相关型。散发性伯基特淋巴瘤在西方人群中是一种罕见的恶性肿瘤。本报告描述了一例颌骨散发性伯基特淋巴瘤病例,其扩散速度惊人且伴有急性肾衰竭。这种快速进展表明牙科医生需要及时识别并进行挽救生命的转诊。累及颌骨的伯基特淋巴瘤的临床特征包括牙齿严重活动过度、异位移位和萌出过高。本病例报告及文献复习的目的是阐述伯基特淋巴瘤的临床和组织病理学特征,以帮助临床医生轻松识别此类病例,并促进及时且可能挽救生命的转诊。