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口腔原发性伯基特淋巴瘤。两例报告、文献综述及牙科意义

The Primary Outbreaks of Burkitt Lymphoma in the Oral Cavity. A Report of Two Cases, Review of the Literature and Dental Implications.

作者信息

Kulczyk Tomasz, Daktera-Micker Agata, Biedziak Barbara, Wziątek Agnieszka, Bednarek-Rajewska Katarzyna

机构信息

Department of Diagnostics, Poznan University of Medical Sciences, Bukowska 70, 60-812 Poznan, Poland.

Department of Craniofacial Anomalies, Poznan University of Medical Sciences, 60-812 Poznan, Poland.

出版信息

Diagnostics (Basel). 2021 Dec 14;11(12):2358. doi: 10.3390/diagnostics11122358.

Abstract

Two cases of Sporadic Burkitt's lymphoma in children aged 11 and 8 years with primary symptoms in the oral cavity are reported. The first symptoms of the disease appeared in the oral cavity and were initially misdiagnosed as an inflammatory condition in one case and incidental findings not associated with the primary reason for visiting the dentist's office in the second case. Biopsies of the lesions revealed the actual cause of the observed changes and contributed to the prompt initiation of polychemotherapy treatment. A review of current literature presents the known symptoms of Burkitt's Lymphoma in the oral cavity and the available diagnostic methods. The role of the primary care physicians-the pedodontist and paediatrician-in the diagnostic and therapeutic process is discussed.

摘要

报告了两例11岁和8岁儿童散发性伯基特淋巴瘤,首发症状均在口腔。该疾病的首发症状出现在口腔,其中一例最初被误诊为炎症,另一例则是在看牙医时偶然发现,最初未被认为与就诊的主要原因相关。病变活检揭示了观察到的变化的实际原因,并促使迅速开始多药化疗。对当前文献的综述介绍了口腔伯基特淋巴瘤的已知症状和可用的诊断方法。讨论了初级保健医生——儿童牙医和儿科医生——在诊断和治疗过程中的作用。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ca37/8700466/0a6ac9038d52/diagnostics-11-02358-g001.jpg

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