Segger D, Schönlau F
Skin Investigation and Technology, 20354 Hamburg, Germany.
J Dermatolog Treat. 2004 Jul;15(4):222-6. doi: 10.1080/09546630410033772.
To investigate whether nutritional intervention with a proprietary formulation and other micronutrients may favourably alter skin roughness and elasticity.
Sixty-two women aged 45-73 years participated in a double-blind, placebo-controlled trial testing the efficacy of a proprietary oral supplement for skin nutrition (Evelle), for improvement of skin elasticity and roughness. The active ingredients were vitamins C and E, carotenoids, selenium, zinc, amino acids and glycosaminoglycans, blueberry extract and Pycnogenol.
Skin elasticity, measured using an optical cutometer, was found to be statistically significantly increased by 9% after 6 weeks of treatment compared with placebo (p=0.0351). Skin roughness, as evaluated by three-dimensional microtopography imaging, was found to be statistically significantly lowered by 6% compared with the control group after 12 weeks treatment (p=0.0157).
Evelle can potentially improve visible signs of cutaneous ageing.
研究使用一种专利配方及其他微量营养素进行营养干预是否能有效改善皮肤粗糙度和弹性。
62名年龄在45 - 73岁的女性参与了一项双盲、安慰剂对照试验，以测试一种用于皮肤营养的专利口服补充剂（Evelle）改善皮肤弹性和粗糙度的功效。其活性成分包括维生素C和E、类胡萝卜素、硒、锌、氨基酸和糖胺聚糖、蓝莓提取物和碧萝芷。
使用光学皮肤弹性测定仪测量发现，治疗6周后，与安慰剂组相比，皮肤弹性在统计学上显著提高了9%（p = 0.0351）。通过三维微观形貌成像评估发现，治疗12周后，与对照组相比，皮肤粗糙度在统计学上显著降低了6%（p = 0.0157）。
Evelle可能改善皮肤衰老的可见迹象。
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