Melville Jennifer L, Katon Wayne, Delaney Kristin, Newton Katherine
Department of Obstetrics and Gynecology, University of Washington School of Medicine, Box 356460, 1959 NE Pacific Street, Seattle, WA 98195-6460, USA.
Arch Intern Med. 2005 Mar 14;165(5):537-42. doi: 10.1001/archinte.165.5.537.
Urinary incontinence (UI) is a common disorder that is increasingly important as our population ages. Less is known about UI in younger women, and few large surveys have been able to determine risk factors by linking their data to patients' medical findings.
We conducted a population-based, age-stratified postal survey of 6000 women aged between 30 and 90 years who were enrolled in a large health maintenance organization in Washington State.
The response rate was 64% (n = 3536) after exclusion criteria were applied. The population-based prevalence of UI was 45%. Prevalence increased with age, from 28% for 30- to 39-year-old women to 55% for 80- to 90-year-old women. Eighteen percent of respondents reported severe UI. The prevalence of severe UI also increased notably with age, from 8% for 30- to 39-year-old women to 33% for 80- to 90-year-old women. Older age, higher body mass index (BMI, calculated as weight in kilograms divided by the square of height in meters), greater medical comorbidity, current major depression, a history of hysterectomy, and parity increased the odds of having UI. Not being white and having had only cesarean deliveries decreased the odds of having UI. Major depression (odds ratio, 2.48; 95% confidence interval, 1.65-3.72) and obesity, defined as having a BMI of 30 or greater (odds ratio, 2.39; 95% confidence interval, 1.99-2.87), had the strongest association with UI. Among women with UI, age, BMI, medical comorbidity, current major depression, diabetes, a history of hysterectomy, and having had only cesarean deliveries were significantly associated with severe UI.
Urinary incontinence is highly prevalent in women across their adult life span, and its severity increases linearly with age. Age, BMI, race, medical comorbidity, current major depression, a history of hysterectomy, parity, and having only had cesarean deliveries are each independent factors significantly associated with the likelihood of having UI.
尿失禁(UI)是一种常见疾病,随着人口老龄化,其重要性日益凸显。对于年轻女性的尿失禁情况了解较少,且很少有大型调查能够通过将数据与患者的医学检查结果相联系来确定危险因素。
我们对华盛顿州一家大型健康维护组织中6000名年龄在30至90岁之间的女性进行了一项基于人群的、按年龄分层的邮政调查。
应用排除标准后,回复率为64%(n = 3536)。基于人群的尿失禁患病率为45%。患病率随年龄增长而增加,30至39岁女性为28%,80至90岁女性为55%。18%的受访者报告有严重尿失禁。严重尿失禁的患病率也随年龄显著增加,30至39岁女性为8%,80至90岁女性为33%。年龄较大、体重指数(BMI,计算方法为体重(千克)除以身高(米)的平方)较高、合并症较多、当前患有重度抑郁症、有子宫切除术史以及多产增加了患尿失禁的几率。非白人以及仅通过剖宫产分娩降低了患尿失禁的几率。重度抑郁症(比值比,2.48;95%置信区间,1.65 - 3.72)和肥胖(定义为BMI为30或更高,比值比,2.39;95%置信区间,1.99 - 2.87)与尿失禁的关联最为密切。在患有尿失禁的女性中,年龄、BMI、合并症、当前重度抑郁症、糖尿病、子宫切除术史以及仅通过剖宫产分娩与严重尿失禁显著相关。
尿失禁在成年女性中非常普遍,其严重程度随年龄呈线性增加。年龄、BMI、种族、合并症、当前重度抑郁症、子宫切除术史、产次以及仅通过剖宫产分娩均是与患尿失禁可能性显著相关的独立因素。