感染艾滋病毒儿童的心脏功能障碍：一项试点研究。

Cardiac dysfunction in HIV infected children: a pilot study.

作者信息

Shah Ira, Prabhu S S, V Sumitra, Shashikiran H S

机构信息

Department of Pediatric Cardiology and Pediatric HIV Clinic, Bai Jerbai Wadia Hospital for Children, Acharya Dhonde Marg, Parel, Mumbai 400 012, India.

出版信息

Indian Pediatr. 2005 Feb;42(2):146-9.

PMID:15767710

Abstract

Twenty six perinatally acquired HAART naive HIV positive children asymptomatic for cardiac disease in age group of 1-9 years were evaluated for cardiac abnormalities by echocardiography. All children were classified according to the revised CDC classification for HIV infection in children. 20 (76.9 percent) patients had evidence of cardiac abnormalities on echocardiography. 18 (69.2 percent) patients in category B had statistically significant abnormal echocardiographic finding . The commonest echocardiographic abnormalities seen were left ventricular dilatation in 10 (38.5 percent) and left ventricular hypertrophy in 10 (38.5 percent) patients. Echocardiographic abnormalities are present even in HIV-infected children who are asymptomatic for cardiac dysfunction.

摘要

对26名年龄在1至9岁、围产期感染艾滋病毒且未接受过高效抗逆转录病毒治疗（HAART）、无心脏疾病症状的儿童进行了超声心动图检查，以评估心脏异常情况。所有儿童均根据修订后的美国疾病控制与预防中心（CDC）儿童HIV感染分类标准进行分类。20名（76.9%）患者在超声心动图检查中有心脏异常的证据。B类中的18名（69.2%）患者有统计学上显著的异常超声心动图表现。最常见的超声心动图异常是10名（38.5%）患者出现左心室扩张，10名（38.5%）患者出现左心室肥厚。即使在无心脏功能障碍症状的艾滋病毒感染儿童中也存在超声心动图异常。