Sun X W
Cancer Institute, Harbin Medical College, Heilongjiang.
Zhonghua Zhong Liu Za Zhi. 1992 Nov;13(6):413-5.
Recently, lung cancer has become the first cause of death in women of Harbin. Although 90% of this cancer in man could be attributed to smoking, the etiological factors for women lung cancer still remain obscure. A case-control study consisting of 418 female lung cancer patients and 398 controls was conducted from 1985-1987. The purpose of this study was to evaluate the relevancy of heating fuels and respiratory diseases in the development of lung cancer in women. After having adjusted for smoking, soft coal (OR = 2.26, 95% CI 1.53-3.33) and brazier (OR = 1.36, 95% CI 1.01-1.83) were found to increase the risk of female lung cancer. There was an obvious time-effect in the use of soft coal in relation to female lung cancer (TRND mean = 14.49, P less than 0.001). As to the past history of respiratory diseases, both pulmonary tuberculosis (OR = 1.81) and pulmonary emphysema (OR = 2.29) increased the risk of female lung cancer.
最近,肺癌已成为哈尔滨女性的首要死因。尽管男性肺癌的90%可归因于吸烟,但女性肺癌的病因仍不清楚。1985年至1987年进行了一项病例对照研究,包括418名女性肺癌患者和398名对照。本研究的目的是评估取暖燃料和呼吸系统疾病与女性肺癌发生的相关性。在对吸烟进行校正后,发现使用软煤(比值比=2.26,95%可信区间1.53-3.33)和火盆(比值比=1.36,95%可信区间1.01-1.83)会增加女性患肺癌的风险。使用软煤与女性肺癌之间存在明显的时间效应(趋势检验均值=14.49,P<0.001)。至于呼吸系统疾病的既往史,肺结核(比值比=1.81)和肺气肿(比值比=2.29)都会增加女性患肺癌的风险。