Bell Brian D, Fine Jason, Dow Christian, Seidenberg Michael, Hermann Bruce P
Department of Neurology, University of Wisconsin-Madison, Madison, WI 53792, USA.
Psychol Assess. 2005 Mar;17(1):103-9. doi: 10.1037/1040-3590.17.1.103.
Conventional memory assessment may fail to identify memory dysfunction characterized by intact recall for a relatively brief period but rapid forgetting thereafter. This study assessed learning and retention after 30-min and 24-hr delays on auditory and visual selective reminding tests (SRTs) in right (n=20) and left (n=22) temporal lobe epilepsy (TLE) patients and controls (n=49). The left TLE group performed significantly worse than controls on all 3 trials of both tests. The right TLE group differed from the controls on all 3 visual SRT trials and on learning for the auditory SRT. There were no between-groups differences in rate of information lost at the 30-min versus the 24-hr delay. At the individual level, there was no difference in the percentage of patients versus controls who demonstrated isolated memory impairment at the 24-hr delay. Accelerated forgetting over 24 hr is uncommon in TLE patients.
其特征是在相对较短的时间段内回忆完好，但随后迅速遗忘。本研究评估了右侧（n = 20）和左侧（n = 22）颞叶癫痫（TLE）患者及对照组（n = 49）在听觉和视觉选择性提醒测试（SRT）中延迟30分钟和24小时后的学习和记忆保持情况。左侧TLE组在两项测试的所有3次试验中表现均显著差于对照组。右侧TLE组在所有3次视觉SRT试验以及听觉SRT学习方面与对照组存在差异。在30分钟与24小时延迟时信息丢失率在组间无差异。在个体水平上，在24小时延迟时出现孤立性记忆损害的患者与对照组的百分比无差异。TLE患者在24小时内加速遗忘的情况并不常见。
