[老年原发性高血压患者大动脉扩张性的临床研究]
[Clinical study of the distensibility of large arteries in elderly patients with essential hypertension].
作者信息
Zhang Zhi-Mian, Liang Ji-le, Gao Hai-Qing, Li Man, Gao Xi-Mei, Mi Feng-Hua, Chen Min
机构信息
Department of Geriatrics, Qilu Hospital, Shandong University, Jinan 250012, China.
出版信息
Zhonghua Liu Xing Bing Xue Za Zhi. 2004 Dec;25(12):1068-9.
OBJECTIVE
To explore the change in the distensibility of large arteries and its influencing factors in elderly patients with essential hypertension.
METHODS
Automatic measuring system for pulse wave velocity (PWV) was applied to examine carotid-femoral PWV as an index reflecting distensibility of large arteries. 118 hypertensive patients aged 64 - 83 (mean age 67.12 +/- 10.26) years were included in the study. Of them, 87 were males and 31 were females.
RESULTS
PWV of 118 hypertensive patients increased with increasing age (P < 0.001). Multivariate regressive analysis demonstrated that age and systolic blood pressure had the close relationship with PWV (P < 0.001).
CONCLUSION
Hypertension of the elderly could cause reduction of distensibility of large arteries. Age and systolic blood pressure had the close relationship with distensibility of large arteries in elderly patients with essential hypertension.
目的
探讨老年原发性高血压患者大动脉扩张性的变化及其影响因素。
方法
应用脉搏波速度（PWV）自动测量系统检测颈股动脉PWV，作为反映大动脉扩张性的指标。本研究纳入了118例年龄在64 - 83岁（平均年龄67.12 +/- 10.26岁）的高血压患者。其中，男性87例，女性31例。
结果
118例高血压患者的PWV随年龄增长而升高（P < 0.001）。多因素回归分析表明，年龄和收缩压与PWV密切相关（P < 0.001）。
结论
老年高血压可导致大动脉扩张性降低。年龄和收缩压与老年原发性高血压患者大动脉扩张性密切相关。
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