Glassman Steven D, Berven Sigurd, Bridwell Keith, Horton William, Dimar John R
Department of Orthopaedic Surgery, University of Louisville School of Medicine and the Kenton D. Leatherman Spine Center, Louisville, KY, USA.
Spine (Phila Pa 1976). 2005 Mar 15;30(6):682-8. doi: 10.1097/01.brs.0000155425.04536.f7.
This study is a retrospective review of the initial enrollment data from a prospective multicentered study of adult spinal deformity.
The purpose of this study is to correlate radiographic measures of deformity with patient-based outcome measures in adult scoliosis.
Prior studies of adult scoliosis have attempted to correlate radiographic appearance and clinical symptoms, but it has proven difficult to predict health status based on radiographic measures of deformity alone. The ability to correlate radiographic measures of deformity with symptoms would be useful for decision-making and surgical planning.
The study correlates radiographic measures of deformity with scores on the Short Form-12, Scoliosis Research Society-29, and Oswestry profiles. Radiographic evaluation was performed according to an established positioning protocol for anteroposterior and lateral 36-inch standing radiographs. Radiographic parameters studied were curve type, curve location, curve magnitude, coronal balance, sagittal balance, apical rotation, and rotatory subluxation.
The 298 patients studied include 172 with no prior surgery and 126 who had undergone prior spine fusion. Positive sagittal balance was the most reliable predictor of clinical symptoms in both patient groups. Thoracolumbar and lumbar curves generated less favorable scores than thoracic curves in both patient groups. Significant coronal imbalance of greater than 4 cm was associated with deterioration in pain and function scores for unoperated patients but not in patients with previous surgery.
This study suggests that restoration of a more normal sagittal balance is the critical goal for any reconstructive spine surgery. The study suggests that magnitude of coronal deformity and extent of coronal correction are less critical parameters.
本研究是对一项关于成人脊柱畸形的前瞻性多中心研究的初始入组数据进行回顾性分析。
本研究旨在将成人脊柱侧凸畸形的影像学测量指标与基于患者的结局指标进行关联。
既往关于成人脊柱侧凸的研究试图将影像学表现与临床症状相关联,但事实证明仅基于畸形的影像学测量来预测健康状况是困难的。将畸形的影像学测量指标与症状相关联的能力对于决策和手术规划将是有用的。
本研究将畸形的影像学测量指标与简短健康调查问卷12项版本、脊柱侧凸研究学会29项问卷及奥斯威斯功能障碍指数的评分进行关联。根据既定的前后位和侧位36英寸站立位X线片定位方案进行影像学评估。研究的影像学参数包括曲线类型、曲线位置、曲线大小、冠状面平衡、矢状面平衡、顶椎旋转和旋转半脱位。
所研究的298例患者中,172例未曾接受过手术,126例曾接受过脊柱融合手术。矢状面平衡为正值是两组患者临床症状最可靠的预测指标。在两组患者中,胸腰段和腰段曲线产生的评分均不如胸段曲线。对于未接受手术的患者,大于4 cm的显著冠状面失衡与疼痛和功能评分恶化相关,但在既往接受过手术的患者中并非如此。
本研究表明,恢复更正常的矢状面平衡是任何脊柱重建手术的关键目标。该研究表明,冠状面畸形的程度和冠状面矫正的范围是不太关键的参数。