Mutijima E, Hmissa S, Ziadi S, Mlaiki A, Mokni M, Korbi S
Université de Liège, Département d'Anatomie et Cytologie Pathologiques.
Rev Med Liege. 2005 Jan;60(1):41-4.
Extramedullary hematopoiesis (EMH) is a common manifestation in beta-thalassemia, but can also occur in several clinical hematologic disorders or neoplasms. It has been reported in almost all sites of the body. Often asymptomatic, it can be manifested by compression of the adjacent organs. Spinal cord compression as a consequence of EMH in the intraspinal epidural space is an extremely rare complication. We report a case of a 34 year old man who was hospitalised for complete paraplegia and spasticity of both lower limbs; spinal cord compression on D4-D8 by EMH was diagnosed by MRI and confirmed by histologic examination.
髓外造血(EMH)是β地中海贫血的常见表现,但也可发生于多种临床血液系统疾病或肿瘤中。几乎在身体的所有部位均有报道。它通常无症状,可表现为对邻近器官的压迫。脊髓硬膜外间隙的EMH导致脊髓压迫是一种极其罕见的并发症。我们报告一例34岁男性患者,因双下肢完全性截瘫和痉挛入院;通过MRI诊断为EMH导致的D4 - D8节段脊髓压迫,并经组织学检查证实。