来自毛叶蛇菰的二氢查耳酮葡萄糖苷的没食子酰、咖啡酰和六羟基二苯甲酰酯
Galloyl, caffeoyl and hexahydroxydiphenoyl esters of dihydrochalcone glucosides from Balanophora tobiracola.
作者信息
Tanaka Takashi, Uehara Rami, Nishida Kaori, Kouno Isao
机构信息
Graduate School of Biomedical Sciences, Nagasaki University, 1-14 Bunkyo-machi, Nagasaki 852-8521, Japan.
出版信息
Phytochemistry. 2005 Mar;66(6):675-81. doi: 10.1016/j.phytochem.2004.10.018.
Seven galloyl, caffeoyl and (S)-hexahydroxydiphenoyl (HHDP) esters of dihydrochalcone glucosides were isolated from Balanophora tobiracola; based on spectroscopic and chemical evidence, their structures were determined to be 6''-O-galloyl-, 3'',4''-di-O-galloyl-, 4'',6''-di-O-galloyl-, 4'',6''-O-(S)-HHDP-, 3''-O-galloyl-4'',6''-O-(S)-HHDP-, 3''-O-caffeoyl-4'',6''-O-(S)-HHDP-3-hydroxyphloretin 4'-O-beta-D-glucosides and 3''-O-galloyl-4'',6''-O-(S)-HHDP-phloretin 4'-O-beta-D-glucoside, respectively. By contrast, these compounds were not found in the taxonomically related B. japonica. The 3''-galloyl-4'',6''-HHDP esters of the dihydrochalcone glucosides showed strong inhibitory activities against alpha-glucosidase. Four known compounds were also isolated namely, (+/-)-eriodictyol 7-O-beta-D-glucoside, 1-O-caffeoyl-3-O-galloyl-beta-D-glucose, phloretin 4'-O-beta-D-glucoside, and 3-hydroxyphloretin 4'-O-beta-D-glucoside.
从日本蛇菰中分离出了七种二氢查耳酮葡萄糖苷的没食子酰、咖啡酰和（S）-六羟基二苯甲酰（HHDP）酯；基于光谱和化学证据，确定它们的结构分别为6''-O-没食子酰基-、3''，4''-二-O-没食子酰基-、4''，6''-二-O-没食子酰基-、4''，6''-O-（S）-HHDP-、3''-O-没食子酰基-4''，6''-O-（S）-HHDP-、3''-O-咖啡酰基-4''，6''-O-（S）-HHDP-3-羟基根皮素4'-O-β-D-葡萄糖苷和3''-O-没食子酰基-4''，6''-O-（S）-HHDP-根皮素4'-O-β-D-葡萄糖苷。相比之下，在分类学上相关的日本蛇菰中未发现这些化合物。二氢查耳酮葡萄糖苷的3''-没食子酰基-4''，6''-HHDP酯对α-葡萄糖苷酶表现出较强的抑制活性。还分离出了四种已知化合物，即（±）-圣草酚7-O-β-D-葡萄糖苷、1-O-咖啡酰基-3-O-没食子酰基-β-D-葡萄糖、根皮素4'-O-β-D-葡萄糖苷和3-羟基根皮素4'-O-β-D-葡萄糖苷。
Zotero 插件