漫射光学成像的最新进展

Recent advances in diffuse optical imaging.

作者信息

Gibson A P, Hebden J C, Arridge S R

机构信息

Department of Medical Physics and Bioengineering, University College London, UK.

出版信息

Phys Med Biol. 2005 Feb 21;50(4):R1-43. doi: 10.1088/0031-9155/50/4/r01.

DOI:10.1088/0031-9155/50/4/r01

PMID:15773619

Abstract

We review the current state-of-the-art of diffuse optical imaging, which is an emerging technique for functional imaging of biological tissue. It involves generating images using measurements of visible or near-infrared light scattered across large (greater than several centimetres) thicknesses of tissue. We discuss recent advances in experimental methods and instrumentation, and examine new theoretical techniques applied to modelling and image reconstruction. We review recent work on in vivo applications including imaging the breast and brain, and examine future challenges.

摘要

我们回顾了漫射光学成像的当前技术水平，这是一种用于生物组织功能成像的新兴技术。它涉及通过测量在较大（大于几厘米）厚度的组织中散射的可见光或近红外光来生成图像。我们讨论了实验方法和仪器的最新进展，并研究了应用于建模和图像重建的新理论技术。我们回顾了最近在体内应用方面的工作，包括对乳房和大脑的成像，并探讨了未来的挑战。