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[类风湿关节炎中的骨质疏松与骨折]

[Osteoporosis and fracture in rheumatoid arthritis].

作者信息

Norimatsu H

机构信息

Department of Orthopedic Surgery, Kagawa Medical University.

出版信息

Clin Calcium. 2001 May;11(5):589-92.

Abstract

Patients with rheumatoid arthritis often have periarticular and generalized osteoporosis. Bone resorption develops through increased productions of cytokines and prostaglandines by synovium and bone. Important risk factors of osteoporosis are functional impairment, postmenopausal state, and corticosteroids usage. Osteoporotic fracture occurs at the spinal body, femoral neck, distal radius, and periprosthetic bone.

摘要

类风湿性关节炎患者常伴有关节周围及全身性骨质疏松。骨吸收通过滑膜和骨中细胞因子及前列腺素生成增加而发展。骨质疏松的重要危险因素包括功能障碍、绝经后状态和使用皮质类固醇。骨质疏松性骨折发生于椎体、股骨颈、桡骨远端和假体周围骨。

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