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医院层面急性心肌梗死治疗及预后的种族差异

Hospital-level racial disparities in acute myocardial infarction treatment and outcomes.

作者信息

Barnato Amber E, Lucas F Lee, Staiger Douglas, Wennberg David E, Chandra Amitabh

机构信息

Department of Medicine, School of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania 15213, USA.

出版信息

Med Care. 2005 Apr;43(4):308-19. doi: 10.1097/01.mlr.0000156848.62086.06.

Abstract

BACKGROUND

Previous studies have documented racial disparities in treatment of acute myocardial infarction (AMI) among Medicare beneficiaries. However, the extent to which unobserved differences between hospitals explains some of these differences is unknown.

OBJECTIVE

The objective of this study was to determine whether the observed racial treatment disparities for AMI narrow when analyses account for differences in where blacks and whites are hospitalized.

RESEARCH DESIGN

Retrospective observational cohort study using Medicare claims and medical record review.

SUBJECTS

This study included 130,709 white and 8286 black Medicare patients treated in 4690 hospitals in 50 US states for confirmed AMI in 1994 and 1995.

MEASURES

Measures in this study were receipt of reperfusion, aspirin, and smoking cessation counseling during hospitalization; prescription of aspirin, angiotensin-converting enzyme inhibitor, and beta-blocker at hospital discharge; receipt of cardiac catheterization, percutaneous coronary intervention (PCI), or bypass surgery (CABG) within 30 days of AMI; and 30-day and 1-year mortality.

RESULTS

Within-hospital analyses narrowed or erased black-white disparities for medical treatments received during the acute hospitalization, widened black-white disparities for follow-up surgical treatments, and augmented the survival advantage among blacks. These findings indicate that, on average, blacks went to hospitals that had lower rates of evidence-based medical treatments, higher rates of cardiac procedures, and worse risk-adjusted mortality after AMI.

CONCLUSIONS

Incorporating the hospital effect altered the findings of racial disparity analyses in AMI and explained more of the disparities than race. A policy of targeted hospital-level interventions may be required for success of national efforts to reduce disparities.

摘要

背景

先前的研究记录了医疗保险受益人中急性心肌梗死(AMI)治疗方面的种族差异。然而,医院间未被观察到的差异在多大程度上解释了其中一些差异尚不清楚。

目的

本研究的目的是确定当分析考虑黑人和白人住院地点的差异时,观察到的 AMI 种族治疗差异是否会缩小。

研究设计

使用医疗保险理赔数据和病历审查的回顾性观察队列研究。

研究对象

本研究纳入了 1994 年和 1995 年在美国 50 个州的 4690 家医院接受确诊 AMI 治疗的 130709 名白人医疗保险患者和 8286 名黑人医疗保险患者。

测量指标

本研究的测量指标包括住院期间接受再灌注治疗、阿司匹林治疗和戒烟咨询;出院时开具阿司匹林、血管紧张素转换酶抑制剂和β受体阻滞剂;AMI 后 30 天内接受心脏导管插入术、经皮冠状动脉介入治疗(PCI)或搭桥手术(CABG);以及 30 天和 1 年死亡率。

结果

医院内部分析缩小或消除了急性住院期间接受的医疗治疗方面的黑白差异,扩大了后续手术治疗方面的黑白差异,并增强了黑人的生存优势。这些发现表明,平均而言,黑人前往的医院基于证据的医疗治疗率较低、心脏手术率较高且 AMI 后风险调整死亡率较差。

结论

纳入医院效应改变了 AMI 种族差异分析的结果,并且比种族因素解释了更多的差异。为了国家减少差异的努力取得成功,可能需要采取有针对性的医院层面干预政策。

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