Fu Ting-Ying, Wang Jyh-Seng, Tseng Hui-Hwa
Department of Pathology and Laboratory Medicine, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan, ROC.
J Chin Med Assoc. 2004 Dec;67(12):629-32.
Acute perforated appendicitis is a very rare initial presentation of appendiceal lymphoma. A case of primary lymphoma of the appendix in a 42-year-old female is reported here. The symptom was pain in the right lower quadrant of the abdomen. Surgical intervention was performed under clinical diagnosis of acute appendicitis. Grossly, the resected appendix was gangrenous and perforated. Light microscopy revealed transmural infiltration by diffuse large B-cell lymphoma with angioinvasion and tumor necrosis, resulting in perforated acute suppurative appendicitis. To the best of our knowledge, only 4 cases of well-documented primary diffuse large B-cell lymphoma of appendix have been reported in the world literature.
急性穿孔性阑尾炎是阑尾淋巴瘤极为罕见的首发表现。本文报道了一例42岁女性原发性阑尾淋巴瘤病例。症状为右下腹部疼痛。在临床诊断为急性阑尾炎的情况下进行了手术干预。大体上，切除的阑尾呈坏疽并穿孔。光镜检查显示弥漫性大B细胞淋巴瘤透壁浸润伴血管侵犯和肿瘤坏死，导致穿孔性急性化脓性阑尾炎。据我们所知，世界文献中仅报道了4例有充分记录的原发性阑尾弥漫性大B细胞淋巴瘤病例。
