Ho Suzanne C, Chen Yu-ming, Woo Jean L F
Department of Community and Family Medicine, Chinese University of Hong Kong, Hong Kong Special Administrative Region, People's Republic of China.
Am J Epidemiol. 2005 Apr 1;161(7):680-90. doi: 10.1093/aje/kwi047.
Many studies have shown that better education is favorable for lowering the risks for a number of chronic diseases, but little information is available on the relation with bone health. The authors examined the association of educational level, classified as levels I-IV, with bone mineral density (BMD) and with the prevalence of osteoporosis among 685 population-based, postmenopausal, Chinese women aged 48-63 years during 1999-2001. They observed a significant dose-response positive relation between educational level and BMDs at the total-body (p = 0.011), lumbar spine, and hip sites (p < 0.001) after adjusting for age, years since menopause, and body weight. Mean BMDs of educational level IV women were higher by 4.2-11.9% at the various sites compared with level I women (analysis of covariance, p < 0.05). Similarly, the authors also observed a significant inverse dose-response relation between educational level and prevalence of osteoporosis. Women of educational level I were 3.5-8.6 times more likely to be osteoporotic compared with those of level IV at the various sites. The proportion of BMD or osteoporosis variations accounted for by educational level was attenuated by about 40% after further controlling for potentially explanatory covariates. In conclusion, a higher level of education is independently associated with better BMDs and lower prevalence of osteoporosis among postmenopausal Chinese women.
许多研究表明,接受更好的教育有利于降低多种慢性病的风险,但关于其与骨骼健康的关系却知之甚少。作者在1999年至2001年期间,对685名48至63岁、以社区为基础的绝经后中国女性,研究了分为I-IV级的教育水平与骨密度(BMD)以及骨质疏松症患病率之间的关联。在调整年龄、绝经年限和体重后,他们观察到教育水平与全身(p = 0.011)、腰椎和髋部部位的骨密度之间存在显著的剂量反应正相关(p < 0.001)。与I级教育水平的女性相比,IV级教育水平的女性在各个部位的平均骨密度高4.2%-11.9%(协方差分析,p < 0.05)。同样,作者还观察到教育水平与骨质疏松症患病率之间存在显著的反向剂量反应关系。在各个部位,I级教育水平的女性患骨质疏松症的可能性是IV级女性的3.5-8.6倍。在进一步控制潜在的解释性协变量后,教育水平所解释的骨密度或骨质疏松症变异比例降低了约40%。总之,较高的教育水平与绝经后中国女性更好的骨密度和较低的骨质疏松症患病率独立相关。