[Pancreatic endocrine function in patients with acute pancreatitis].

The secretory function of the pancreas is also impaired in acute destructive pancreatitis. A four- to five-fold increase of serum insulin and glucagon concentrations during the development of the disease is evidence in favor of the development of pancreonecrosis. Diabetic, type disorders of glucose tolerance were encountered in 38% of patients with acute pancreatitis, the clinical form of diabetes mellitus was found in 8.3% of the examined patients.