Olszewski S, Kinalska I, Długosz J, Stasiewicz J, Gabryelewicz A
Endokrinologie. 1978 Apr;71(2):183-91.
In 25 patients having a history of acute pancreatitis (AP) in anamnesis one year ago and in 12 control subjects the insulin response to oral glucose was investigated and in some cases the exocrine function of pancreas was evaluated. The disturbances in glucose tolerance occurred in about 30% of the patients and were associated with impairment of insulin response and deterioration of exocrine pancreatic function. The double cortisone and glucose load did not influence the glucose tolerance in the patients. In persons investigated during AP and one year later only slight improvement of insulin response was noted. The results support the significance of follow-up studies of carbohydrate tolerance and insulin response in patients after AP for the evaluation of the diabetic risk in such cases.
在25例一年前有急性胰腺炎（AP）病史的患者及12名对照者中，研究了口服葡萄糖后的胰岛素反应，部分病例还评估了胰腺的外分泌功能。约30%的患者出现糖耐量异常，且与胰岛素反应受损及胰腺外分泌功能恶化有关。双皮质醇和葡萄糖负荷对患者的糖耐量无影响。在急性胰腺炎期间及之后一年接受调查的患者中，仅观察到胰岛素反应略有改善。这些结果支持对急性胰腺炎患者进行碳水化合物耐量和胰岛素反应随访研究对于评估此类病例糖尿病风险的重要性。
