Anti-estrogenic activity of lignans from Acanthopanax chiisanensis root.
作者信息
Lee Sanghyun, Yoo Hye Hyun, Piao Xiang Lan, Kim Ju Sun, Kang Sam Sik, Shin Kuk Hyun
机构信息
College of Pharmacy, Seoul National University, Seoul 151-742, Korea.
出版信息
Arch Pharm Res. 2005 Feb;28(2):186-9. doi: 10.1007/BF02977713.
PMID:15789749
Abstract
Anti-estrogenic activity of (-)-sesamin (1), helioxanthin (2), savinin (3), taiwanin C (4), and 3-(3,4-dimethoxybenzyl)-2-(3,4-methylenedioxybenzyl)butyrolactone (5) isolated from the root of Acanthopanax chiisanensis was tested using Ishikawa cells. Among them, compound 3 exhibited anti-estrogenic activity (IC50 = 4.86 microM).
摘要
Zotero 插件