Morris Luc G, Burschtin Omar, Lebowitz Richard A, Jacobs Joseph B, Lee Kelvin C
Department of Otolaryngology-Head and Neck Surgery, New York University School of Medicine, New York, New York 10016, USA.
Am J Rhinol. 2005 Jan-Feb;19(1):33-9.
The relationship between nasal airway function and sleep-disordered breathing (SDB) remains unclear. Although correction of nasal obstruction can significantly improve nighttime breathing in some patients, nasal obstruction may not play a role in all cases of SDB. An effective method of stratifying these patients is needed. Acoustic rhinometry (AR) is a reliable, noninvasive method of measuring the dimensions of the nasal airway.
In 44 patients, we performed acoustic rhinometric measurements of nasal airway cross-sectional area, followed by hospital-based polysomnography and nasal continuous positive airway pressure (nCPAP) level titration. We compared anatomic nasal obstruction to perceived nasal obstruction, as well as respiratory distress index and nCPAP titration level, using the Pearson correlation and multiple linear regression analysis within body mass index groups.
Perceived nasal obstruction correlated significantly with objective anatomic obstruction as measured by AR (r = 0.45, p < 0.01). For certain subgroup analyses in patients with a body mass index below 25, AR measurements correlated significantly with both nCPAP titration pressure (r = 0.85, p < 0.01) and respiratory distress index (r = 0.67, p = 0,03).
Nasal airway function may be a significant component of SDB in some patients, perhaps playing a larger role in patients who are not overweight. The best responders to nasal surgery for SDB may be nonoverweight patients with nasal obstruction. AR along with nasal examination may be helpful in the evaluation and treatment of the SDB patient.
鼻气道功能与睡眠呼吸障碍(SDB)之间的关系仍不明确。尽管矫正鼻阻塞可显著改善部分患者的夜间呼吸,但鼻阻塞可能并非在所有SDB病例中都起作用。需要一种有效的方法对这些患者进行分层。鼻声反射测量法(AR)是一种可靠的、非侵入性的测量鼻气道尺寸的方法。
我们对44例患者进行了鼻气道横截面积的鼻声反射测量,随后进行了基于医院的多导睡眠监测和鼻持续气道正压通气(nCPAP)水平滴定。我们在体重指数组内使用Pearson相关性分析和多元线性回归分析,比较了解剖学上的鼻阻塞与感知到的鼻阻塞,以及呼吸窘迫指数和nCPAP滴定水平。
感知到的鼻阻塞与通过AR测量的客观解剖学阻塞显著相关(r = 0.45,p < 0.01)。在体重指数低于25的患者进行的某些亚组分析中,AR测量结果与nCPAP滴定压力(r = 0.85,p < 0.01)和呼吸窘迫指数(r = 0.67,p = 0.03)均显著相关。
鼻气道功能可能是部分患者SDB的一个重要组成部分,在体重正常的患者中可能起更大作用。SDB鼻手术最佳反应者可能是体重正常的鼻阻塞患者。AR联合鼻检查可能有助于SDB患者的评估和治疗。