Miyazaki Yoshiko, Kusano Shuichi, Doi Hiroshi, Aki Osami
Department of Food Science and Nutrition, School of Human Environmental Sciences, Institute for Biosciences, Mukogawa Women's University, Hyogo, Japan.
Nutrition. 2005 Mar;21(3):358-62. doi: 10.1016/j.nut.2004.11.001.
The present report describes the effects of antidiabetic ingredients from white-skinned sweet potato (AWSSP) on the immune response of human cells.
We studied the effects of inactive Staphylococcus aureus cells coated with AWSSP on phagocytic activity, phagosome-lysosome fusion, and superoxide anion release by human leukocytes in vitro.
AWSSP increased phagocytic activity and phagosome-lysosome fusion in neutrophils and monocytes in a dose-dependent manner. In contrast, AWSSP had no significant effect on superoxide anion release (O2-) from human neutrophils.
These results show that AWSSP is useful in the prevention and improvement of diabetic symptoms by stimulating human immunity and that Ipomoea batatas L. is a beneficial food because it increases immune activity in addition to its antidiabetic effects.
本报告描述了白薯抗糖尿病成分（AWSSP）对人体细胞免疫反应的影响。
我们研究了包被有AWSSP的无活性金黄色葡萄球菌细胞对人白细胞体外吞噬活性、吞噬体-溶酶体融合及超氧阴离子释放的影响。
AWSSP以剂量依赖方式增强中性粒细胞和单核细胞的吞噬活性及吞噬体-溶酶体融合。相比之下，AWSSP对人中性粒细胞的超氧阴离子（O2-）释放无显著影响。
这些结果表明，AWSSP通过刺激人体免疫力对糖尿病症状的预防和改善有用，且甘薯除具有抗糖尿病作用外还能增强免疫活性，是一种有益食品。
