白皮甘薯（Ipomoea batatas L.）抗糖尿病成分对免疫反应的影响。
Effects on immune response of antidiabetic ingredients from white-skinned sweet potato (Ipomoea batatas L.).
作者信息
Miyazaki Yoshiko, Kusano Shuichi, Doi Hiroshi, Aki Osami
机构信息
Department of Food Science and Nutrition, School of Human Environmental Sciences, Institute for Biosciences, Mukogawa Women's University, Hyogo, Japan.
出版信息
Nutrition. 2005 Mar;21(3):358-62. doi: 10.1016/j.nut.2004.11.001.
OBJECTIVES
The present report describes the effects of antidiabetic ingredients from white-skinned sweet potato (AWSSP) on the immune response of human cells.
METHODS
We studied the effects of inactive Staphylococcus aureus cells coated with AWSSP on phagocytic activity, phagosome-lysosome fusion, and superoxide anion release by human leukocytes in vitro.
RESULTS
AWSSP increased phagocytic activity and phagosome-lysosome fusion in neutrophils and monocytes in a dose-dependent manner. In contrast, AWSSP had no significant effect on superoxide anion release (O2-) from human neutrophils.
CONCLUSIONS
These results show that AWSSP is useful in the prevention and improvement of diabetic symptoms by stimulating human immunity and that Ipomoea batatas L. is a beneficial food because it increases immune activity in addition to its antidiabetic effects.
目的
本报告描述了白薯抗糖尿病成分（AWSSP）对人体细胞免疫反应的影响。
方法
我们研究了包被有AWSSP的无活性金黄色葡萄球菌细胞对人白细胞体外吞噬活性、吞噬体-溶酶体融合及超氧阴离子释放的影响。
结果
AWSSP以剂量依赖方式增强中性粒细胞和单核细胞的吞噬活性及吞噬体-溶酶体融合。相比之下，AWSSP对人中性粒细胞的超氧阴离子（O2-）释放无显著影响。
结论
这些结果表明，AWSSP通过刺激人体免疫力对糖尿病症状的预防和改善有用，且甘薯除具有抗糖尿病作用外还能增强免疫活性，是一种有益食品。
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