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恶性颅咽管瘤对基于顺铂的化疗有显著反应。颅咽管瘤应被视为鞍上“生殖细胞”肿瘤吗?

Dramatic response of malignant craniopharyngioma to cis-platin-based chemotherapy. Should craniopharyngioma be considered as a suprasellar 'germ cell' tumour?

作者信息

Plowman P N, Besser G M, Shipley J, Summersgill B, Geddes J, Afshar F

机构信息

Department of Clinical Oncology, St Bartholomew's Hospital, London, UK.

出版信息

Br J Neurosurg. 2004 Oct;18(5):500-5. doi: 10.1080/02688690400012400.

DOI:10.1080/02688690400012400
PMID:15799153
Abstract

The case is described of a 21-year-old woman, who developed a malignant tumour arising from a craniopharyngioma 14 years after the original diagnosis. The remarkable response of this malignant tumour ex-craniopharyngioma to cis-platin based chemotherapy, together with other midline tumour characteristics of craniopharyngioma, raise the question as to whether craniopharyngioma should any longer be separately considered from suprasellar germ cell tumour. This subject is discussed.

摘要

本文描述了一名21岁女性的病例,该患者在最初诊断为颅咽管瘤14年后发生了起源于颅咽管瘤的恶性肿瘤。这种颅咽管瘤恶变后的恶性肿瘤对基于顺铂的化疗有显著反应,再加上颅咽管瘤的其他中线肿瘤特征,引发了一个问题,即颅咽管瘤是否应不再与鞍上生殖细胞瘤分开考虑。本文对此进行了讨论。

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