颅咽管瘤的恶性转化

Malignant transformation in craniopharyngioma.

作者信息

Nelson G A, Bastian F O, Schlitt M, White R L

机构信息

Department of Pathology, University of South Alabama Medical Center, Mobile.

出版信息

Neurosurgery. 1988 Feb;22(2):427-9. doi: 10.1227/00006123-198802000-00029.

DOI:10.1227/00006123-198802000-00029

PMID:3352897

Abstract

Malignant transformation in a craniopharyngioma has not been described previously. A 49-year-old woman presented with recurrence of a suprasellar craniopharyngioma diagnosed 35 years previously. The patient had been treated surgically for recurrence on five occasions. Radiation therapy had been administered 7 years before the final presentation. Tissue obtained from the fifth operation revealed malignant degeneration in a typical craniopharyngioma.

摘要

颅咽管瘤的恶性转化此前尚未见报道。一名49岁女性，出现了35年前诊断的鞍上颅咽管瘤复发。该患者因复发已接受了5次手术治疗。在最后一次就诊前7年曾接受过放射治疗。第五次手术获取的组织显示，典型的颅咽管瘤发生了恶性退变。