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阴囊外佩吉特病。1例伴有局部淋巴结转移。

Extramammary Paget's disease of scrotum. A case with local lymph node metastasis.

作者信息

Parada David, Moreira Otto, López Carmen, Rodríguez Jhonny, Marín Maria Elena, Farías Rosa M

机构信息

Service of Pathology, Vargas Hospital, Caracas, Venezuela.

出版信息

Arch Esp Urol. 2005 Jan-Feb;58(1):85-9. doi: 10.4321/s0004-06142005000100015.

DOI:10.4321/s0004-06142005000100015
PMID:15801657
Abstract

OBJECTIVE

We describe the clinical, histological and immunohistochemical studies in a case of extramammary Paget's disease localized in the scrotum with lymph node inguinal metastasis.

METHODS/RESULTS: A 80-year old man consulted with a one-year history of a pruritic erythematous skin rash of the scrotum. Physical examination showed demarcated erythematous lesion involving the scrotum and right inguinal adenopathy. Final histological examination revealed extramammary Paget's disease with inguinal metastasis.

CONCLUSION

Extramammary Paget's disease of the scrotum is a rare disease. This pathological condition may spread to dermal region and the regional lymph nodes. Although genitourinary cancer may accompany scrotal extramammary Paget's disease, an extensive search for cancer may be unnecessary.

摘要

目的

我们描述了一例阴囊部乳腺外佩吉特病伴腹股沟淋巴结转移的临床、组织学及免疫组化研究。

方法/结果:一名80岁男性因阴囊部瘙痒性红斑皮疹病史一年前来就诊。体格检查发现界限清楚的红斑病变累及阴囊及右侧腹股沟淋巴结肿大。最终组织学检查显示为乳腺外佩吉特病伴腹股沟转移。

结论

阴囊部乳腺外佩吉特病是一种罕见疾病。这种病理状况可能扩散至真皮区域及区域淋巴结。虽然泌尿生殖系统癌症可能伴随阴囊部乳腺外佩吉特病,但可能无需进行广泛的癌症筛查。

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Extramammary Paget's disease of scrotum. A case with local lymph node metastasis.阴囊外佩吉特病。1例伴有局部淋巴结转移。
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Genitourinary extramammary Paget's disease: review and outcome in a multidisciplinary setting.泌尿生殖系统乳腺外佩吉特病:多学科背景下的综述与转归
Int J Clin Exp Pathol. 2020 Sep 1;13(9):2369-2376. eCollection 2020.
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A case of metastatic adenocarcinoma on a background of penoscrotal extramammary Paget's disease.阴茎阴囊部乳腺外佩吉特病背景下的转移性腺癌1例。
BMJ Case Rep. 2015 Sep 30;2015:bcr2015211350. doi: 10.1136/bcr-2015-211350.