Ishige Takeru, Honda Kohsuke, Shimizu Sakayu
Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Kitashirakawa-Oiwakecho, Sakyo-ku, Kyoto 606-8502, Japan.
Curr Opin Chem Biol. 2005 Apr;9(2):174-80. doi: 10.1016/j.cbpa.2005.02.001.
The use of biocatalysts for the industrial synthesis of chemicals has been attracting much attention as an environment-friendly synthetic method. Microbial cells play a leading role in 'chemo-enzymatic synthesis' because of their great diversity. Several microbes with unique catalytic abilities have been found through intensive screening and put to practical use. Besides, advanced molecular biological techniques are powerful tools for developing more satisfactory biocatalysts.
作为一种环境友好型合成方法，使用生物催化剂进行化学品的工业合成一直备受关注。微生物细胞因其多样性在“化学酶法合成”中发挥着主导作用。通过深入筛选已发现了几种具有独特催化能力的微生物并将其投入实际应用。此外，先进的分子生物学技术是开发更理想生物催化剂的有力工具。
