Slob Marjan J, van Rooij Willem Jan, Sluzewski Menno
Department of Radiology, St. Elisabeth Ziekenhuis, Tilburg, Netherlands.
AJNR Am J Neuroradiol. 2005 Apr;26(4):901-3.
In coiling cerebral aneurysms, high packing prevents reopening over time. The purpose of this study was to compare packing of cerebral aneurysms treated with two types of coils with different wire thickness and different shapes.
Packing, defined as the ratio between the volume of inserted coils and the volume of an aneurysm, was calculated for 144 cerebral aneurysms treated in 130 patients. Seventy-two aneurysms were treated with predominantly helical-shaped coils of 0.010-inch-diameter wire, and 72 aneurysms were treated with predominantly complex-shaped coils of 0.012-inch-diameter wire. Aneurysm volume was assessed from three-dimensional angiography. Aneurysm packing, inserted coil lengths, and numbers of coils were compared for both types of coils.
Mean packing was significantly higher (absolute value, 6.4%; relative value, 26.6%; P < .0001) in aneurysms coiled with 0.012-inch-diameter coils than aneurysms coiled with 0.010-inch-diameter coils. Inserted coil length per cubic millimeter of aneurysmal volume was equal for both types of coils.
Use of complex-shaped coils with a wire diameter of 0.012 inch to coil cerebral aneurysms results in significantly better packing than is achieved with helical coils of 0.010-inch-diameter wire.
在脑动脉瘤的弹簧圈栓塞治疗中，高填充率可防止动脉瘤随时间复发。本研究的目的是比较使用两种不同线径和不同形状的弹簧圈治疗脑动脉瘤的填充情况。
计算了130例患者中144个脑动脉瘤的填充率，填充率定义为插入弹簧圈的体积与动脉瘤体积之比。72个动脉瘤主要采用直径0.010英寸的螺旋形弹簧圈治疗，72个动脉瘤主要采用直径0.012英寸的复杂形状弹簧圈治疗。通过三维血管造影评估动脉瘤体积。比较了两种弹簧圈的动脉瘤填充率、插入弹簧圈长度和弹簧圈数量。
使用直径0.012英寸弹簧圈栓塞的动脉瘤平均填充率显著更高（绝对值6.4%；相对值26.6%；P <.0001），高于使用直径0.010英寸弹簧圈栓塞的动脉瘤。两种弹簧圈每立方毫米动脉瘤体积的插入弹簧圈长度相等。
使用直径0.012英寸的复杂形状弹簧圈栓塞脑动脉瘤，其填充效果明显优于使用直径0.010英寸的螺旋形弹簧圈。
