Lee Ok-Jun, Kim Hyun Jung, Lee Bu Kyu, Cho Kyung-Ja
Department of Pathology, Chunbuk National University Hospital, Cheongju, Korea.
J Oral Pathol Med. 2005 May;34(5):318-20. doi: 10.1111/j.1600-0714.2005.00309.x.
Ameloblastic fibrosarcoma (AFS) is a rare malignant tumor of the jaw. The malignant mesenchymal component of AFS has been described as 'fibroblast-like', although little is known about the immunophenotype, except for vimentin expression. Here, we present a case of AFS in a 62-year-old woman. The mesenchymal component displayed the features of either dermatofibrosarcoma protuberans or fibrosarcoma, and was positive for CD34. This is the first reported case of CD34 expressing AFS in the maxilla.
成釉细胞纤维肉瘤（AFS）是一种罕见的颌骨恶性肿瘤。AFS的恶性间充质成分被描述为“成纤维细胞样”，尽管除波形蛋白表达外，对其免疫表型知之甚少。在此，我们报告一例62岁女性的AFS病例。间充质成分表现出隆突性皮肤纤维肉瘤或纤维肉瘤的特征，且CD34呈阳性。这是上颌骨中首例报道的表达CD34的AFS病例。
