Guha Roy S, Bhisey A N
Cancer Research Institute, Tata Memorial Centre, Parel, India.
Cell Biol Int Rep. 1992 Mar;16(3):269-81. doi: 10.1016/s0309-1651(06)80128-1.
Nucleation of microtubule (MT) organization of the cytoplasmic microtubule complex (CMTC) from the microtubule organizing centres (MTOC) was studied in enucleated cytoplasts of human diploid fibroblast (MRC-5) and mouse peritoneal macrophages in culture. Cytoplasts of both cell types could not organize the complete CMTC. Aberrant MT patterns were seen in MRC-5 cells while mouse macrophages showed occurrence of few short MT. The studies suggest that nucleus may have a role in determining CMTC.
在培养的人二倍体成纤维细胞（MRC - 5）和小鼠腹腔巨噬细胞的去核细胞质体中，研究了来自微管组织中心（MTOC）的细胞质微管复合体（CMTC）的微管（MT）成核情况。两种细胞类型的细胞质体都无法组织完整的CMTC。在MRC - 5细胞中观察到异常的MT模式，而小鼠巨噬细胞则显示出少量短MT的出现。这些研究表明，细胞核可能在决定CMTC方面发挥作用。
