Tendolkar Indira, Ruhrmann Stephan, Brockhaus-Dumke Anke, Pauli Monika, Mueller Ralf, Pukrop Ralf, Klosterkötter Joachim
Department of Psychiatry and Psychotherapy, University of Cologne, Cologne, Germany.
Int J Neurosci. 2005 May;115(5):681-98. doi: 10.1080/00207450590887475.
The authors investigated the role of visuo-spatial attention in an antisaccade task using event-related potentials (ERPs) in schizophrenia patients compared to healthy controls. ERPs between 80-130 ms (P100) after stimulus onset showed differences between pro- and antisaccades only for controls and can be related to the suppression of irrelevant stimulus features. Between 150-180 ms (N100), a larger amplitude for anti-compared to prosaccades over centroparietal electrodes showed that processes of visuo-spatial attention seem to be engaged in performance of the antisaccade task. Left temporo-occipitally, this activity was only evident in schizophrenia patients, possibly reflecting additional neuronal recruitment in order to perform the antisaccade task successfully.
作者使用事件相关电位（ERP）研究了视觉空间注意力在精神分裂症患者与健康对照者反扫视任务中的作用。刺激开始后80 - 130毫秒（P100）之间的ERP仅在对照组的顺向和反扫视之间显示出差异，这可能与无关刺激特征的抑制有关。在150 - 180毫秒（N100）之间，中央顶叶电极上反扫视相对于顺向扫视的振幅更大，这表明视觉空间注意力过程似乎参与了反扫视任务的执行。在左侧颞枕叶区域，这种活动仅在精神分裂症患者中明显，这可能反映了为成功执行反扫视任务而额外募集的神经元。
