Hone J, Pech R, Yip P
Applied Ecology Research Group, University of Canberra, Australia.
Epidemiol Infect. 1992 Apr;108(2):377-86. doi: 10.1017/s0950268800049840.
Infectious diseases establish in a population of wildlife hosts when the number of secondary infections is greater than or equal to one. To estimate whether establishment will occur requires extensive experience or a mathematical model of disease dynamics and estimates of the parameters of the disease model. The latter approach is explored here. Methods for estimating key model parameters, the transmission coefficient (beta) and the basic reproductive rate (RDRS), are described using classical swine fever (hog cholera) in wild pigs as an example. The tentative results indicate that an acute infection of classical swine fever will establish in a small population of wild pigs. Data required for estimation of disease transmission rates are reviewed and sources of bias and alternative methods discussed. A comprehensive evaluation of the biases and efficiencies of the methods is needed.
当二代感染数量大于或等于1时,传染病会在野生动物宿主群体中传播开来。要估计传染病是否会传播开来,需要丰富的经验,或者疾病动态数学模型以及疾病模型参数的估计值。本文探讨的是后一种方法。以野猪的经典猪瘟(猪霍乱)为例,描述了估计关键模型参数——传播系数(β)和基本繁殖率(RDRS)的方法。初步结果表明,经典猪瘟的急性感染会在一小群野猪中传播开来。本文回顾了估计疾病传播率所需的数据,并讨论了偏差来源和替代方法。需要对这些方法的偏差和效率进行全面评估。