Corwin Andrew L, Subekti Decy, Sukri Nono C, Willy Ronald J, Master John, Priyanto Eko, Laras Kanti
U.S. Naval Medical Research Unit No. 2, Jakarta, Indonesia.
Am J Trop Med Hyg. 2005 Apr;72(4):488-94.
An outbreak of acute diarrheal disease was reported in Kupang, Nusa Tenggara, Indonesia, in August 2002. An investigative team carried out a retrospective historical review of records, and a case-control study involving data and specimen collections. Etiologic determination involving stool specimens was based on an enzyme-linked immunosorbent assay, with a reverse transcriptase-polymerase chain reaction performed for serotyping purposes. Two thousand six hundred probable cases were identified from hospital records during the outbreak months of June, July, August, and September 2002. Previous enteric outbreaks were recognized from the same months in the preceding years and all annual outbreak episodes following a period of prolonged, low rainfall. In contrast to previous outbreaks discerned from trend analysis, the overwhelming burden of disease fell upon the pediatric population versus the young and old in previous outbreak instances. Rotavirus was found to be the causative etiology, with serotype 1 predominating.
2002年8月，印度尼西亚努沙登加拉省古邦市报告了一起急性腹泻病疫情。一个调查小组对记录进行了回顾性历史审查，并开展了一项涉及数据和样本收集的病例对照研究。对粪便样本进行的病因鉴定基于酶联免疫吸附测定，并进行逆转录聚合酶链反应以进行血清分型。在2002年6月、7月、8月和9月的疫情期间，从医院记录中确定了2600例可能病例。在前几年的同一月份以及经过一段长时间少雨期后的所有年度疫情中，都发现了以前的肠道疫情。与趋势分析中发现的以前的疫情相比，此次疾病的主要负担落在了儿童群体身上，而在以前的疫情中，负担主要落在年轻人和老年人身上。发现轮状病毒是病因，其中1型血清型占主导。
