[老年疗养院中由轮状病毒G9P[8]引起的肠胃炎暴发的检测]
[Detection of a rotavirus G9P[8] outbreak causing gastroenteritis in a geriatric nursing home].
作者信息
Sanz Juan Carlos, Barbas José Francisco, Lasheras María Dolores, Jiménez Mariana, Ramos Belén, Sánchez-Fauquier Alicia
机构信息
Laboratorio Regional de Salud Pública, Instituto de Salud Pública de la Comunidad de Madrid, Madrid, España.
出版信息
Enferm Infecc Microbiol Clin. 2009 Apr;27(4):219-21. doi: 10.1016/j.eimc.2008.06.005. Epub 2009 Feb 26.
INTRODUCTION
The aim of this study was to describe an outbreak of gastroenteritis due to rotavirus in a geriatric nursing home.
METHOD
Stool samples from 8 patients were studied. Antigen detection was carried out by ELISA, and molecular typing was performed by RT-PCR.
RESULTS
Rotavirus antigen was detected in 6 patients. Typing demonstrated a common genotype (G9P[8]).
CONCLUSION
The outbreak detected in elderly persons suggests a loss of immunity with age or a lack of protection against an emergent genotype.
引言
本研究旨在描述一家老年疗养院中由轮状病毒引起的胃肠炎暴发情况。
方法
对8例患者的粪便样本进行了研究。通过酶联免疫吸附测定法进行抗原检测，并通过逆转录聚合酶链反应进行分子分型。
结果
在6例患者中检测到轮状病毒抗原。分型显示为一种常见基因型（G9P[8]）。
结论
在老年人中检测到的此次暴发提示随着年龄增长免疫力丧失或缺乏针对新出现基因型的保护。
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