甘露糖结合凝集素：我们需要它吗？
Mannose-binding lectin: do we need it?
作者信息
Klein N J
机构信息
Infectious Diseases and Microbiology Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK.
出版信息
Mol Immunol. 2005 May;42(8):919-24. doi: 10.1016/j.molimm.2004.12.006. Epub 2005 Jan 26.
PMID:15829282
Abstract
Mannose-binding lectin (MBL) deficiency has now been recognised for 15 years. Numerous studies have shown that MBL deficiency is associated with an increased susceptibility to a range of infections. However, the importance of MBL, in defence against infection, is still debated. This article discusses recent developments in MBL research and explores how MBL may be operating in the setting of modern medical practice.
摘要
甘露糖结合凝集素（MBL）缺陷现已被认识15年了。大量研究表明，MBL缺陷与一系列感染易感性增加有关。然而，MBL在抗感染防御中的重要性仍存在争议。本文讨论了MBL研究的最新进展，并探讨了MBL在现代医学实践背景下可能发挥作用的方式。
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