Price Cathy J, Mechelli Andrea
Wellcome Department of Imaging Neuroscience, Institute of Neurology, 12, Queen Square, London, WC1N 3BG, UK.
Curr Opin Neurobiol. 2005 Apr;15(2):231-8. doi: 10.1016/j.conb.2005.03.003.
Recent functional neuroimaging studies are generating novel insights into our knowledge of skilled and disturbed reading. In neurologically normal subjects, a double dissociation in neural activation in response to reading words and pseudowords has been revealed that corresponds to that observed in the comparison of semantic and phonological tasks. In patients with acquired dyslexia, functional imaging is demonstrating re-organisation within the reading system; in developmental dyslexia, functional imaging is being used to identify the impact of rehabilitation. Together, these findings have implications for cognitive models of reading that have previously relied on input from behavioural data.
最近的功能性神经影像学研究为我们对熟练阅读和阅读障碍的认识带来了新的见解。在神经功能正常的受试者中,已揭示出对单词和假词阅读的神经激活存在双重分离,这与语义和语音任务比较中观察到的情况相对应。在获得性阅读障碍患者中,功能成像显示了阅读系统内的重新组织;在发育性阅读障碍中,功能成像正被用于确定康复的影响。这些发现共同对以前依赖行为数据输入的阅读认知模型产生了影响。