Okada Susumu, Ohaki Yoshiharu, Inoue Kohei, Kawamura Takashi, Hayashi Toshihiko, Kato Tomoyasu, Kumazaki Tatsuo
Department of Radiology, Nippon Medical School Chiba-Hokuso Hospital, Inba-gun, Chiba 270-1694, Japan.
J Nippon Med Sch. 2005 Feb;72(1):29-33. doi: 10.1272/jnms.72.29.
Mucinous cystic ovarian tumors sometimes contain calcifications, but the frequency and significance of such calcifications in diagnostic radiology are not well understood. We therefore retrospectively investigated the radiological and histopathological evidence of calcifications in 44 cases of ovarian mucinous cystic tumors (22 benign, 13 borderline, and 9 malignant) and 21 cases of ovarian serous cystic tumors (6 benign and 15 malignant) in which a non-contrast CT scan was performed. The shape and distribution of the calcifications in the mass lesion were assessed both radiologically and histopathologically. Calcifications were noted in 34.1% of mucinous cystic tumors on CT scans and 56.8% in histopathological studies, and they were found in two locations, intramural and intra-cystic, according to the histopathological findings. Intramural calcifications were frequent in benign tumors, and intra-cystic calcifications were frequent in proliferating tumors. Calcifications (psammoma bodies) were noted in 4.7% of serous cystic tumors on CT scans and 14.3% in histopathological studies. CT was not sufficiently sensitive in the detection of intra-cystic calcification in mucinous tumors and psammoma bodies in serous tumors. However, the presence of intramural calcifications may be a good indicator of mucinous tumors. Understanding the frequency and morphology of the calcifications in these neoplasms is one of the keys to making a correct diagnosis.
黏液性卵巢囊肿性肿瘤有时含有钙化灶，但在诊断放射学中，此类钙化灶的发生率及意义尚未完全明确。因此，我们回顾性研究了44例卵巢黏液性囊肿性肿瘤（22例良性、13例交界性和9例恶性）及21例卵巢浆液性囊肿性肿瘤（6例良性和15例恶性）的钙化灶的放射学和组织病理学证据，这些病例均进行了非增强CT扫描。从放射学和组织病理学两方面评估了肿块病变中钙化灶的形态和分布。CT扫描显示，黏液性囊肿性肿瘤中34.1%存在钙化灶，组织病理学研究显示为56.8%；根据组织病理学结果，钙化灶存在于两个部位，即壁内和囊内。壁内钙化在良性肿瘤中较为常见，囊内钙化在增殖性肿瘤中较为常见。CT扫描显示，浆液性囊肿性肿瘤中4.7%存在钙化灶（砂粒体），组织病理学研究显示为14.3%。CT对黏液性肿瘤囊内钙化及浆液性肿瘤砂粒体的检测敏感性不足。然而，壁内钙化的存在可能是黏液性肿瘤的一个良好指标。了解这些肿瘤中钙化灶的发生率和形态是做出正确诊断的关键之一。
