Siech M, Tripp K, Schmidt-Rohlfing B, Mattfeldt T, Widmaier U, Gansauge F, Görich J, Beger H G
Department of General Surgery, University of Ulm, Germany.
Langenbecks Arch Surg. 1998 Mar;383(1):56-61. doi: 10.1007/s004230050092.
Cystic neoplasms of the pancreas account for only 1% of primary pancreatic lesions. However, patients with these tumors are diagnosed more frequently. Up to now, nonsurgical management is still the established form of treatment of benign cystic tumours of the pancreas.
Between 1987 and 1996 we treated 51 patients with serous and mucinous cystadenoma and their malignant counterparts, serous and mucinous cystadenocarcinoma.
Eighty-five percent of the patients presented symptoms. Computed tomography and endoscopic cholangiopancreatography (ERCP) were the most sensitive diagnostic techniques; however, in three patients with serous cystadenoma and in one patient with serous cystadenocarcinoma, ERCP findings were completely normal. The tumour was resected in all but one patient. There was no perioperative mortality. After dismissal from the hospital, all patients in whom benign tumours had been resected are still alive; however, the late mortality of mucinous cystadenocarcinoma was 36% after a median follow-up of 6 years.
Surgical resection is recommended in all cystic tumours, even in serous cystic tumours, because symptoms may develop and malignant transformation to serous cystadenocarcinoma is possible.
胰腺囊性肿瘤仅占胰腺原发性病变的1%。然而，这些肿瘤患者的诊断频率更高。到目前为止，非手术治疗仍然是胰腺良性囊性肿瘤的既定治疗方式。
1987年至1996年间，我们治疗了51例浆液性和黏液性囊腺瘤及其恶性对应物，即浆液性和黏液性囊腺癌患者。
85%的患者出现症状。计算机断层扫描和内镜逆行胰胆管造影（ERCP）是最敏感的诊断技术；然而，3例浆液性囊腺瘤患者和1例浆液性囊腺癌患者的ERCP检查结果完全正常。除1例患者外，所有患者均接受了肿瘤切除。无围手术期死亡。出院后，所有切除良性肿瘤的患者均存活；然而，黏液性囊腺癌的中位随访6年后的晚期死亡率为36%。
所有囊性肿瘤，即使是浆液性囊性肿瘤，均建议手术切除，因为可能会出现症状，且浆液性囊腺癌可能发生恶变。
