Bethke G, Reichart P A
Abteilung für Oralchirurgie und zahnärztliche Röntgenologie, Zentrum für Zahnmedizin, Charité - Universitätsmedizin Berlin, Campus Virchow-Klinikum.
Mund Kiefer Gesichtschir. 2005 May;9(3):152-60. doi: 10.1007/s10006-005-0606-8.
The goal of this study was to develop a clinical index to assess therapy of oral lichen planus (OLP) to be used in comparing the efficacy of two topical glucocorticoids. The clinical severity of non-gingival and gingival lichen planus and their severity from the patients' view were evaluated.
A clinical index for assessing the severity of oral lichen planus is described with which the clinical forms as well as all the varying combinations of forms can be addressed separately. The clinical classification of OLP into six variants according to Andreasen [1] is the basis of the index. The index provides information about the severity of the disease in single regions and in the patient as a whole. The index is subdivided into a basic index as well as supplementary indices, which are optional. The clinical forms and size of OLP are recorded using the basic index, while various form-specific features such as the intensity of whitish pattern or mucosal erythema can be assessed additionally using the supplementary indices. Non-gingival and gingival lichen planus are assigned with their own indices. An index of subjective symptoms consisting of a visual analogue scale and verbal scales is available for describing patient discomfort. There is also a short form of the index (study-region index/one-region index), whereby only a single selected region is assessed.
The index presented here is available as a new method of assessing OLP severity, offering both basic and advanced information for use especially in scientific studies of oral lichen planus.
本研究的目的是开发一种临床指标，用于评估口腔扁平苔藓（OLP）的治疗效果，以比较两种局部糖皮质激素的疗效。评估了非牙龈和牙龈扁平苔藓的临床严重程度以及患者视角下的严重程度。
描述了一种评估口腔扁平苔藓严重程度的临床指标，利用该指标可分别处理临床形式以及所有不同形式的组合。根据安德里亚森[1]将OLP临床分类为六种变体是该指标的基础。该指标提供有关单个区域和患者整体疾病严重程度的信息。该指标分为基本指标和补充指标，补充指标为可选指标。使用基本指标记录OLP的临床形式和大小，同时可使用补充指标额外评估各种特定形式的特征，如白色斑纹强度或黏膜红斑。非牙龈和牙龈扁平苔藓分别有各自的指标。有一个由视觉模拟量表和文字量表组成的主观症状指标，用于描述患者的不适。还有该指标的简短形式（研究区域指标/单区域指标），即仅评估单个选定区域。
本文提出的指标可作为评估OLP严重程度的新方法，尤其为口腔扁平苔藓的科学研究提供基础和进阶信息。
