基于不同量表的口腔扁平苔藓临床评估。
Clinical assessment of oral lichen planus based on different scales.
机构信息
Hospital Morales Meseguer, Clínica Odontológica Universitaria, 2 planta Medicina Oral, Murcia, Spain.
出版信息
Int J Dermatol. 2010 Mar;49(3):272-5. doi: 10.1111/j.1365-4632.2009.04271.x.
BACKGROUND
Different oral lichen planus (OLP) scoring scales have been developed, though none has received unanimous acceptance from all authors. This study involves the clinical application of two symptom and sign measurement scales for assessing OLP.
MATERIAL AND METHOD
One hundred patients were diagnosed clinically and confirmed as having OLP by biopsy, according to the WHO criteria. A visual analog scale (VAS) was applied (0-10) along with two semi-quantitative tests for assessing the symptoms and signs.
RESULTS
The Escudier test yielded an overall site score of 3.8 +/- 1.83 (mean +/- SD), with an activity score of 1.6 +/- 2.59 (mean +/- SD), and a total weighted score of 7.4 +/- 4.78. The pain VAS score was 1.9 +/- 2.06. The Malhotra scale (range 1-7) yielded a maximum total score of 2.9 +/- 1.21, corresponding to grade 1. The Spearman correlation coefficient between the Escudier and Malhotra scales was 0.54 - the difference proving statistically significant (P < 0.001).
CONCLUSION
Uniform OLP scoring system measures need to be adopted.
背景
不同的口腔扁平苔藓（OLP）评分量表已经开发出来，但没有一个得到所有作者的一致认可。本研究涉及两种用于评估 OLP 的症状和体征测量量表的临床应用。
材料和方法
根据世界卫生组织（WHO）标准，100 名患者经临床诊断和活检证实为 OLP。采用视觉模拟评分（VAS）（0-10）以及两种半定量测试来评估症状和体征。
结果
Escudier 测试得出的总部位评分（site score）为 3.8 +/- 1.83（均值 +/- 标准差），活动评分（activity score）为 1.6 +/- 2.59（均值 +/- 标准差），总加权评分（total weighted score）为 7.4 +/- 4.78。疼痛 VAS 评分为 1.9 +/- 2.06。Malhotra 量表（范围 1-7）的最高总分为 2.9 +/- 1.21，对应于 1 级。Escudier 和 Malhotra 量表之间的 Spearman 相关系数为 0.54，差异具有统计学意义（P < 0.001）。
结论
需要采用统一的 OLP 评分系统进行测量。
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