de Giorgi V, Massi D, Sestini S, Alfaioli B, Carelli G, Carli P
Department of Dermatology, University of Florence, Via degli Alfani 37, 50121 Florence, Italy.
Br J Dermatol. 2005 Apr;152(4):787-90. doi: 10.1111/j.1365-2133.2005.06448.x.
The association of contiguous or 'collision' tumours in the same biopsy specimen is not uncommon and is often reported in the literature. The most common association, basal cell carcinoma (BCC) and naevus, is very difficult to diagnose clinically. We describe a 38-year-old woman with a previous history of melanoma, who presented with a modified pigmented lesion of the hip that had begun to change 6 months earlier. Histologically, the lesion was a melanocytic compound naevus and a BCC with a seborrhoeic keratosis. The case was investigated clinically and by focusing on the dermoscopic features and their pathological correlates. Cutaneous collision tumours are extremely difficult to diagnose preoperatively, even with the help of dermoscopy, in particular when one of the lesions is melanocytic.
在同一活检标本中出现相邻或“碰撞性”肿瘤的情况并不罕见,且在文献中常有报道。最常见的组合,即基底细胞癌(BCC)和痣,在临床上很难诊断。我们描述了一名38岁有黑色素瘤病史的女性,她出现了臀部一处色素改变的皮损,该皮损在6个月前开始变化。组织学检查显示,该皮损为复合性黑素细胞痣和伴有脂溢性角化病的基底细胞癌。对该病例进行了临床研究,并着重观察了皮肤镜特征及其病理相关性。皮肤碰撞性肿瘤术前极难诊断,即使借助皮肤镜也很难,尤其是当其中一个皮损为黑素细胞性时。