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直肠癌乙状结肠切除术后粪便失禁的骶神经刺激治疗

Sacral nerve stimulation for faecal incontinence following a rectosigmoid resection for colorectal cancer.

作者信息

Jarrett Michael E D, Matzel Klaus E, Stösser Michael, Christiansen John, Rosen Harald, Kamm Michael A

机构信息

St. Mark's Hospital, London, UK.

出版信息

Int J Colorectal Dis. 2005 Sep;20(5):446-51. doi: 10.1007/s00384-004-0729-7. Epub 2005 Apr 21.

Abstract

INTRODUCTION

Following recto-sigmoid resection some patients may become faecally incontinent and remain so despite conservative treatment. This multicentre prospective study assessed the use of sacral nerve stimulation (SNS) in this group.

METHODS

All patients had more than or equal to 4 days of faecal incontinence for solid or liquid stools over a 21-day period following recto-sigmoid resection for colorectal carcinoma. The operation had to have been deemed curative. They had to have failed pharmacological and biofeedback treatment.

RESULTS

Three male patients met these criteria. One had had a colo-anal and two a colo-rectal anastomosis for rectal carcinoma. All patients had intact internal and external anal sphincters. Two patients had a successful temporary stimulation period and proceeded to permanent implantation. Pre-operative symptom duration was 1 year in the permanently implanted patients. They were followed up for 12 months. SNS improved the number of faecally incontinent episodes in both patients. Ability to defer was improved in both patients from 0--5 min to 5--15 min. The faecal incontinence-specific ASCRS quality of life assessment improved in all four subcategories.

CONCLUSION

This study demonstrates that SNS may be effective in the treatment of patients with faecal incontinence following recto-sigmoid resection if conservative treatment has failed.

摘要

引言

在进行直肠乙状结肠切除术后,一些患者可能会出现大便失禁,且尽管接受了保守治疗,症状仍会持续存在。这项多中心前瞻性研究评估了骶神经刺激(SNS)在该组患者中的应用。

方法

所有患者在因结直肠癌进行直肠乙状结肠切除术后的21天内,有至少4天出现固体或液体粪便的大便失禁情况。手术必须被认为是根治性的。他们必须已经接受过药物和生物反馈治疗但失败。

结果

三名男性患者符合这些标准。一名患者进行了结肠肛管吻合术,两名患者进行了结肠直肠吻合术以治疗直肠癌。所有患者的肛门内、外括约肌均完整。两名患者的临时刺激期成功,并进行了永久性植入。永久性植入患者的术前症状持续时间为1年。他们接受了12个月的随访。SNS改善了两名患者大便失禁发作的次数。两名患者推迟排便的能力从0至5分钟提高到了5至15分钟。在所有四个亚类中,大便失禁特异性的美国结直肠外科医师学会生活质量评估均得到改善。

结论

本研究表明,如果保守治疗失败,SNS可能对直肠乙状结肠切除术后大便失禁的患者有效。

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