Jarrett M E D, Matzel K E, Christiansen J, Baeten C G M I, Rosen H, Bittorf B, Stösser M, Madoff R, Kamm M A
Department of Physiology, St. Mark's Hospital, London, UK.
Br J Surg. 2005 Jun;92(6):734-9. doi: 10.1002/bjs.4859.
This study examined the use of sacral nerve stimulation (SNS) to treat faecal incontinence in patients with partial spinal injury.
Patients selected for SNS had experienced more than one episode of faecal incontinence per week to liquid or solid stool for more than 1 year and had failed maximal conservative treatment. All patients had an intact external anal sphincter.
Temporary SNS was performed in 13 patients (median age 58.5 (range 39-73) years). The spinal insults were disc prolapse (six), trauma (four), spinal stenosis (one) or occurred during neurosurgery (two). Twelve patients (eight women and four men) had successful temporary stimulation and proceeded to permanent implantation. The median follow-up time was 12 (range 6-24) months. The mean(s.d.) number of episodes of incontinence decreased from 9.33(7.64) per week at baseline to 2.39(3.69) at last follow-up (P = 0.012). The number of days per week with incontinence and staining decreased significantly (both P < 0.001). Ability to defer defaecation improved from a median of not being able to defer (range 0-1 min) to being able to defer for 5-15 (range 0 to over 15) min (P = 0.022).
SNS can benefit patients with faecal incontinence following partial spinal injury.
本研究探讨了骶神经刺激(SNS)在部分脊髓损伤患者大便失禁治疗中的应用。
入选SNS治疗的患者每周出现一次以上液体或固体粪便失禁,持续时间超过1年,且最大程度的保守治疗无效。所有患者肛门外括约肌均完整。
13例患者(中位年龄58.5岁(范围39 - 73岁))接受了临时SNS治疗。脊髓损伤原因包括椎间盘突出(6例)、创伤(4例)、椎管狭窄(1例)或神经外科手术中发生的损伤(2例)。12例患者(8名女性和4名男性)临时刺激成功并进行了永久植入。中位随访时间为12个月(范围6 - 24个月)。失禁发作的平均(标准差)次数从基线时的每周9.33(7.64)次降至末次随访时的2.39(3.69)次(P = 0.012)。每周失禁和污染的天数显著减少(均P < 0.001)。排便延迟能力从中位无法延迟(范围0 - 1分钟)改善为能够延迟5 - 15分钟(范围0至超过15分钟)(P = 0.022)。
SNS可使部分脊髓损伤后大便失禁的患者受益。