Ala Thomas A, Berck Lilla G, Popovich Ann M
Center for Alzheimer Disease and Related Disorders, Department of Neurology, Southern Illinois University School of Medicine, Springfield, Illinois, USA.
Am J Alzheimers Dis Other Demen. 2005 Mar-Apr;20(2):119-25. doi: 10.1177/153331750502000202.
We assessed the ability of 73 patients with Alzheimer's disease (AD) to recall important personal information like their names, their caregivers 'names, their addresses, and their telephone numbers. We also assessed their caregivers' awareness of their abilities. There was an association between the abilities of the patients and their Mini-Mental Status Examination (MMSE) scores, with the patients with the lowest MMSE scores making the most errors. Five to 10 percent of the mildest patients were unable to state their addresses and telephone numbers correctly. The caregivers of the patients with intermediate MMSE scores made the most errors in their predictions, with up to 50 percent being incorrect and up to 37 percent overestimating their patients' abilities. We concluded that AD patients lose their ability to provide personal information as their illness progresses. Caregivers of patients with MMSE ranging from 10 to 25 are the most likely to be unaware of their patients' impairment. These findings highlight safety concerns in AD.
我们评估了73名阿尔茨海默病(AD)患者回忆重要个人信息的能力,如他们自己的姓名、护理人员的姓名、住址和电话号码。我们还评估了其护理人员对他们能力的了解程度。患者的能力与其简易精神状态检查表(MMSE)得分之间存在关联,MMSE得分最低的患者错误最多。最轻度患者中有5%至10%无法正确说出自己的住址和电话号码。MMSE得分中等的患者的护理人员在预测时错误最多,高达50%的预测不正确,高达37%的护理人员高估了患者的能力。我们得出结论,随着病情进展,AD患者会丧失提供个人信息的能力。MMSE得分在10至25之间的患者的护理人员最有可能未意识到其患者的损伤情况。这些发现凸显了AD患者的安全问题。