2-芳基-5-取代-2,3-二氢苯并呋喃的快速合成
A rapid synthesis of 2-aryl-5-substituted-2,3-dihydrobenzofurans.
作者信息
Kuethe Jeffrey T, Wong Audrey, Journet Michel, Davies Ian W
机构信息
Department of Process Research, Merck & Co., Inc., P.O. Box 2000, Rahway, New Jersey 07065, USA.
出版信息
J Org Chem. 2005 Apr 29;70(9):3727-9. doi: 10.1021/jo0500941.
PMID:15845016
Abstract
[reaction: see text] An effective strategy has been developed for the rapid and efficient one-pot synthesis of 2-aryl-5-substituted-2,3-dihydrobenzofurans from readily available o-nitrotoluenes and aromatic aldehydes. This strategy allows access to a structurally diverse array of products for further manipulation.
摘要
[反应：见正文] 已开发出一种有效的策略，可从易得的邻硝基甲苯和芳香醛快速高效地一锅法合成2-芳基-5-取代-2,3-二氢苯并呋喃。该策略能够获得结构多样的一系列产物以供进一步操作。
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