取代1,2,4-三唑的高效区域特异性一锅法合成
Efficient and regiospecific one-pot synthesis of substituted 1,2,4-triazoles.
作者信息
Stocks Michael J, Cheshire David R, Reynolds Rachel
机构信息
Department of Medicinal Chemistry, AstraZeneca R&D Charnwood, Bakewell Road, Loughborough, Leics LE11 5RH, United Kingdom.
出版信息
Org Lett. 2004 Aug 19;6(17):2969-71. doi: 10.1021/ol048863a.
PMID:15330660
Abstract
An efficient one-pot, three-component synthesis of substituted 1,2,4-triazoles has been developed, utilizing a wide range of substituted primary amines and acyl hydrazides.
摘要
利用多种取代的伯胺和酰肼，开发了一种高效的一锅三组分合成取代1,2,4-三唑的方法。
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