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[开放性手术与腹腔镜手术治疗穿孔性阑尾炎的比较研究]

[Open versus laparoscopic operation for perforated appendicitis--a comparative study].

作者信息

Kapischke M, Bley K, Tepel J, Schulz T

机构信息

Chirurgische Klinik des Friedrich Ebert Krankenhauses, Neumünster.

出版信息

Zentralbl Chir. 2005 Apr;130(2):137-41. doi: 10.1055/s-2005-836411.

DOI:10.1055/s-2005-836411
PMID:15849658
Abstract

INTRODUCTION

Laparoscopic therapy of complicated appendicitis is still discussed controversially. This retrospective study compared the clinical results of open and laparoscopic appendectomy in a single centre.

PATIENTS AND METHODS

Within a period of three years (1999 to 2001) 493 patients with suspected acute appendicitis were operated prospectively at a German district hospital (250 open appendectomies, 243 laparoscopic appendectomies). Twenty percent of the patients in every group had a complicated appendicitis (48 open, 44 laparoscopic appendectomies) and were analysed retrospectively considering demographic data, operative time, body mass index, preoperative inflammatory parameters (white blood cell count, C-reactive protein and body temperature) and postoperative complication rate.

RESULTS

Both groups were comparable with regard to demographic data. One patient of the laparoscopic group needed an open operation (conversion rate 2.3 %). The body mass index of the laparoscopic group was significantly higher (26.3 vs. 24.1 kg/m(2)). Preoperative white blood cell count, C-reactive protein, body temperature as well as postoperative antibiotic therapy and analgesics requirement were comparable in both groups. There was no significant difference between the length of operative time (open 48 min, laparoscopic 53.5 min). The postoperative hospital stay was significantly shorter in the laparoscopic group (8 vs. 9 days, p = 0.032). Complication rate was significantly lower in the laparoscopic group (11.5 vs. 35 %, p = 0.014).

CONCLUSION

Laparoscopic appendectomy is a safe procedure for the treatment of complicated appendicitis with a significantly decreased complication rate and shorter postoperative stay.

摘要

引言

腹腔镜治疗复杂性阑尾炎仍存在争议。本回顾性研究比较了单中心开放手术和腹腔镜阑尾切除术的临床结果。

患者与方法

在三年时间(1999年至2001年)内,一家德国地区医院对493例疑似急性阑尾炎患者进行了前瞻性手术(250例开放阑尾切除术,243例腹腔镜阑尾切除术)。每组20%的患者患有复杂性阑尾炎(48例开放手术,44例腹腔镜手术),并对其人口统计学数据、手术时间、体重指数、术前炎症参数(白细胞计数、C反应蛋白和体温)及术后并发症发生率进行回顾性分析。

结果

两组在人口统计学数据方面具有可比性。腹腔镜组有1例患者需要转为开放手术(转换率2.3%)。腹腔镜组的体重指数显著更高(26.3 vs. 24.1 kg/m²)。两组术前白细胞计数、C反应蛋白、体温以及术后抗生素治疗和镇痛药需求相当。手术时间长度无显著差异(开放手术48分钟,腹腔镜手术53.5分钟)。腹腔镜组术后住院时间显著更短(8天 vs. 9天,p = 0.032)。腹腔镜组并发症发生率显著更低(11.5% vs. 35%,p = 0.014)。

结论

腹腔镜阑尾切除术是治疗复杂性阑尾炎的一种安全手术,并发症发生率显著降低,术后住院时间更短。

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