Cuvorova I N, Davydov V V, Prozorovskiĭ V N, Shvets V N
Biomed Khim. 2005;51(1):66-71.
The antioxidant action of the extract from Aronia melanocarpa leaves on the brain was investigated. The intraperitoneal injection of extract in the dose of 0.2 g/kg prevented manifestations of oxidative stress in the brain induced by immobilization of rats. In vitro experiments revealed that the extract decreased intensity of ascorbate--and H2O2 -induced lipid and protein peroxidation in the brain homogenates. The most effect of the extract on ascorbate--induced lipid peroxidation was found in the postmitochondrial fraction of brain homogenate.
研究了黑果腺肋花楸叶提取物对大脑的抗氧化作用。以0.2 g/kg的剂量腹腔注射提取物可预防大鼠固定引起的大脑氧化应激表现。体外实验表明，该提取物可降低大脑匀浆中抗坏血酸和过氧化氢诱导的脂质和蛋白质过氧化强度。在大脑匀浆的线粒体后部分中发现该提取物对抗坏血酸诱导的脂质过氧化作用最为显著。
